herbals schisandra

RECND342

Schisandra

Scientific:Schisandra chinensis
Other:Wu Wei Zi

Indications

In Asian medicine, tonifies spleen and lung qi; "astringe the jing".

CNS
• mood and nervous system disorders
- agitation
- anxiety
- insomnia (dream-disturbed sleep)
- irritability
- depression
• poor cognition
- attention deficit hyperactivity disorder (ADHD, ADD)
Alzheimer's disease

Endocrine
• stress
chronic fatigue syndrome (CFS)

Hepatic
• drug-induced hepatitis
• viral hepatitis
• cirrhosis (prevention)
• hepatocellular carcinoma (prevention)

Respiratory
• chronic respiratory complaints
asthma

Reproduction
• sexual dysfunction
- premature ejaculation
- nocturnal emission
- erectile dysfunction (ED)

Cancer
• chemotherapy (adjunctive therapy for drug resistance)
• liver cancer (prevention)

Immune
• viral infections
hepatitis B (HBV)

Urinary system
kidney disease

Actions

adaptogen
astringent
expectorant
hepatoprotective
nootropic
anticancer
antiviral
• MDR pump inhibitor
• nephroprotective
antiinflammatory
antioxidant
• antiaging

Constituents

• Lignans (schizandrin) - hepatoprotective and stimulate liver regeneration

Posology

• Tincture (1:5): 1-4 ml tid
• Decoction (dried powdered root): 1-2 tsp bid

Safety

Cautions: Not recommended for use in acute infections (e.g. colds, influenza, bronchitis, pneumonia).

Interactions

Can decrease hepatoxicity of certain medications.

Multidrug resistance (MDR) - demonstrated to inhibit P-glycoproteins that are responsible for drug resistance in cancers.

References

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Barnes J, Anderson LA, Phillipson JD. Herbal Medicines, 3rd ed. London: Pharmaceutical Press, 2007.

Bone K. Principles and Practice of Phytotherapy. Edinburgh: Churchill Livingstone, 2000.

Bone K. A Clinical Guide to Blending Liquid Herbs: Herbal Formulations for the Individual Patient. St Louis, MO: Churchill Livingstone, 2003.

Brinker F. The Toxicology of Botanical Medicines, 3rd ed. Sandy, Oregon: Eclectic Medical Publications, 2000.

Felter HW, Lloyd JU. King's American Dispensatory. 1898. http://www.ibiblio.org/herbmed/eclectic/kings/main.html. Accessed: August 19, 2006.

Hoffman D. Medical Herbalism. Rochester, Vermont: Healing Arts Press, 2003.

Weiss RF. Herbal Medicine. Beaconsfield, England: Beaconsfield Publishers Ltd, 1988.

Williamson EM, ed. Major Herbs of Ayurveda. Edinburgh: Churchill Livingstone, 2002

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