Similar constituents and actions as Hydrastis canadensis and other Berberis spp. May be less effective than Hydrastis canadensis as an antimicrobial but more cost-effective for digestive complaints and chronic skin conditions.
• poor digestion
• poor elimination causing 'bad blood'
• digestive complaints
• gastric ulcer
• peptic ulcer
• biliary dyskinesia
• non-alcoholic fatty liver disease (NAFLD)
• MDR pump inhibitor
• laxative (mild)
• Isoquinoline alkaloids (e.g. hydrastine, berberine)
• Tincture (1:5 in 40% EtOH): 1-4 ml tid
• Decoction (dried root): 1-2 tsp tid
Contraindications: Pregnancy and lactation (uterine stimulant). Berberine is considered teratogenic.
Caution: Hypertension, gastritis, peptic ulcers.
Hypertension: Caution use due to hypertensive and hypotensive effects; monitor BP regularly.
Gastritis, peptic ulcers: Stimulation of gastric secretions can irritate inflamed mucous membranes; concomitant ingestion of demulcent herbs can help prevent aggravation.
• MDR pump inhibitors - contains a flavolignin that inhibits multi-drug resistance pumps, which are responsible for making bacteria resistant to certain antibiotics and cancer resistant to specific chemotherapeutic agents. Therefore it may be a good adjunctive herb to prevent and/or overcome drug resistance.
• Barbiturate - may potentiate their effects.
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Williamson EM, ed. Major Herbs of Ayurveda. Edinburgh: Churchill Livingstone, 2002
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