• adrenal fatigue
• adreno-corticoid insufficiency
• Addison's disease
• inflammation of GI tract
- gastroesophageal reflux disorder (GERD)
- gastric ulcers
- apthous ulcers
- herpes simplex virus (HSV)
- human immunodeficiency virus (HIV)
- severe acute respiratory syndrome (SARS)
- hepatitis (HAV, HBV, HCV)
- Epstein–Barr virus (EBV) - mononucleosis
• polycystic ovary syndrome (PCOS) - in combo with chinese peony
• menopausal hot flashes
• acne rosacea
• triterpene glycoside (glycyrrhizinic acid, glycyrrhetinic acid)
• Tincture (1:5 in 40% EtOH): 1-3 ml tid
• Decoction (dried powdered root): 0.5-1 tsp tid
• Long-term use: large amounts should not be taken for longer than 6-8 weeks.
• Pseudohyperaldosteronism - chronic use may cause symptoms of hyperaldosteronism including: hypertension, hypokalemia, weak muscles, dizziness, edema.
• Blood pressure - should be used with caution in patients with hypertension.
• Pregnancy & lactation: should be used with caution.
Note: Deglycerized licorice (DGL) does not cause affect cortisol and therefore does not cause pseudohyperaldosteronism. It can not be used to tonify the adrenals but still has benefit for GERD, ulcers and gastritis.
Contra-indicated with the following medication that also cause hypokalemia:
• loop diuretics
• thiazide diuretics
• cardiac glycosides
• antiarrhythmic drugs
Caution in patients taking:
• stimulating laxatives (anthraquinones)
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Bone K. Principles and Practice of Phytotherapy. Edinburgh: Churchill Livingstone, 2000.
Bone K. A Clinical Guide to Blending Liquid Herbs: Herbal Formulations for the Individual Patient. St Louis, MO: Churchill Livingstone, 2003.
Brinker F. The Toxicology of Botanical Medicines, 3rd ed. Sandy, Oregon: Eclectic Medical Publications, 2000.
Felter HW, Lloyd JU. King's American Dispensatory. 1898. http://www.ibiblio.org/herbmed/eclectic/kings/main.html. Accessed: August 19, 2006.
Hoffman D. Medical Herbalism. Rochester, Vermont: Healing Arts Press, 2003.
Weiss RF. Herbal Medicine. Beaconsfield, England: Beaconsfield Publishers Ltd, 1988.
Williamson EM, ed. Major Herbs of Ayurveda. Edinburgh: Churchill Livingstone, 2002
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