One of the most useful antimicrobials and mucous membrane tonics.
• general infection (bacterial, parasitic, fungal)
• infections of the alimentary tract
- gastric ulcer (H. Pylori)†
- infectious diarrhea (dysentery, cholera)
- irritable bowel syndrome (IBS)
• infections of the respiratory system
• infections of the reproductive system
- bacterial vaginosis (Gardnerella, Trichomoniasis)
• skin infections (topical application)
- dermatophytes (tinea)
• infections of the eye
• atonic digestive complaints
- pancreatic insufficiency
• gastric esophageal reflux disease (GERD)†
• Inflammatory bowel disease (IBD)
• biliary insufficiency
- cholelithiasis (gallstones)
- biliary dyskinesia
• chronic skin conditions
• various cancers (adjunctive therapy)
• MDR pump inhibitor
• laxative (mild)
• Isoquinoline alkaloids (e.g. hydrastine, berberine)
• Tincture (1:5 in 60% EtOH): 1-4 ml tid
• Liquid extract (1:1 in 60% EtOH): 0.3-1 ml tid
• Infusion (dried root): 1/2-1 tsp tid
Contraindications: Pregnancy and lactation (uterine stimulant). Berberine is considered teratogenic.
Caution: Hypertension, gastritis, peptic ulcers.
Hypertension: Caution use due to hypertensive and hypotensive effects; monitor BP regularly.
†Gastritis, peptic ulcers: Stimulation of gastric secretions can irritate inflamed mucous membranes; concomitant ingestion of demulcent herbs can help prevent aggravation.
• MDR pump inhibitors - contains a flavolignin that inhibits multi-drug resistance pumps, which are responsible for making bacteria resistant to certain antibiotics and cancer resistant to specific chemotherapeutic agents. Therefore it may be a good adjunctive herb to prevent and/or overcome drug resistance.
• Barbiturate - may potentiate their effects.
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