herbals chelidonium

RECND346

Chelidonium

Scientific:Chelidonium majus
Other:Greater Celandine

Indications

Similar constituents and actions to Hydrastis canadensis and Sanguinaria canadensis; primarily used for spastic digestive discomfort e.g. gallbladder spasms and promote flow of digestive juices (e.g. bile)

Hepatobiliary
• biliary insufficiency
- biliary dyskinesia
- biliary colic (gallbladder spasm)
- cholestasis
- cholelithiasis (gallstones)
- jaundice

Gastrointestinal
• atonic digestive complaints
- dyspepsia
- hypochlorhydria
- pancreatic insufficiency
- colic
- irritable bowel syndrome (IBS)

Dermatologic
• dyscratic conditions caused by 'bad blood'
- hives
- eczema
- psoriasis
- acne
• corns

Infection (topical application)
warts
- verruca
- condyloma
- HPV
• fungal infections
herpes simplex (HSV)

Actions

antispasmodic
analgesic
bitter
stomachic
hepatic
cholagogue
choleretic
expectorant
escharotic
antimicrobial
alterative
antiinflammatory
• laxative (mild)
emmenagogue

Constituents

• Isoquinoline alkaloids (e.g. chelidonine, berberine)
• Flavonolignans

Posology

• Tincture (1:10 in 45% EtOH): 1-2 ml tid
• Infusion (herb): 2 tsp tid
• Decoction (dried root): 1 tsp tid

Safety

Contraindications: Pregnancy and lactation (uterine stimulant); berberine is considered teratogenic.

Long-term use: Hepatotoxicity; monitor liver function.

Drug-induced hepatitis: Reported cases (due to isoquinoline alkaloid exposure).

Liver toxicity: Sanguinarine is hepatoxic.

References

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Barnes J, Anderson LA, Phillipson JD. Herbal Medicines, 3rd ed. London: Pharmaceutical Press, 2007.

Bone K. Principles and Practice of Phytotherapy. Edinburgh: Churchill Livingstone, 2000.

Bone K. A Clinical Guide to Blending Liquid Herbs: Herbal Formulations for the Individual Patient. St Louis, MO: Churchill Livingstone, 2003.

Brinker F. The Toxicology of Botanical Medicines, 3rd ed. Sandy, Oregon: Eclectic Medical Publications, 2000.

Felter HW, Lloyd JU. King's American Dispensatory. 1898. http://www.ibiblio.org/herbmed/eclectic/kings/main.html. Accessed: August 19, 2006.

Hoffman D. Medical Herbalism. Rochester, Vermont: Healing Arts Press, 2003.

Weiss RF. Herbal Medicine. Beaconsfield, England: Beaconsfield Publishers Ltd, 1988.

Williamson EM, ed. Major Herbs of Ayurveda. Edinburgh: Churchill Livingstone, 2002

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