Similar constituents and actions as Hydrastis canadensis but less effective as an antimicrobial. More cost-effective for digestive complaints and chronic skin conditions.
• alterative for chronic skin conditions especially when associated with poor digestion and elimination causing 'bad blood':
• atonic digestive complaints
• gastric ulcer†
• condtions related to cholestasis:
- cholelithiasis (gallstones)
- biliary dyskinesia
• non-alcoholic fatty liver disease (NAFLD)
• parasites (Leishmaniasis)
• MDR pump inhibitor
• laxative (mild)
• Isoquinoline alkaloids (e.g. hydrastine, berberine)
• Tincture (1:5 in 60% EtOH): 1-2 ml tid
• Decoction (dried root): 1 tsp tid
Contraindications: Pregnancy and lactation (uterine stimulant). Berberine is considered teratogenic.
Caution: Hypertension, gastritis, peptic ulcers.
Hypertension: Caution use due to hypertensive and hypotensive effects; monitor BP regularly.
†Gastritis, peptic ulcers: Stimulation of gastric secretions can irritate inflamed mucous membranes; concomitant ingestion of demulcent herbs can help prevent aggravation.
• MDR pump inhibitors - contains a flavolignin that inhibits multi-drug resistance pumps, which are responsible for making bacteria resistant to certain antibiotics and cancer resistant to specific chemotherapeutic agents. Therefore it may be a good adjunctive herb to prevent and/or overcome drug resistance.
• Barbiturate - may potentiate their effects.
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