herbals barberry

RECND345

Barberry

Scientific:Berberis vulgaris
Other:Barberry

Indications

Similar constituents and actions as Hydrastis canadensis but less effective as an antimicrobial. More cost-effective for digestive complaints and chronic skin conditions.

Dermatologic
alterative for chronic skin conditions especially when associated with poor digestion and elimination causing 'bad blood':
- hives
- eczema
- psoriasis
- acne

Gastrointestinal
• atonic digestive complaints
- dyspepsia
- hypochlorhydria
gastric ulcer
• colitis

Hepatobiliary
• condtions related to cholestasis:
- cholelithiasis (gallstones)
- dyspepsia
- cholecystitis
- biliary dyskinesia
• non-alcoholic fatty liver disease (NAFLD)

Infection
• bacteria
• yeast
• viruses
• parasites (Leishmaniasis)

Actions

bitter
stomachic
hepatic
cholagogue
choleretic
alterative
• MDR pump inhibitor
antimicrobial
antibacterial
antifungal
antiparasitic
• antileishmanial
antiinflammatory
hepatoprotective
• laxative (mild)
emmenagogue

Constituents

• Isoquinoline alkaloids (e.g. hydrastine, berberine)
• Flavonolignans

Posology

• Tincture (1:5 in 60% EtOH): 1-2 ml tid
• Decoction (dried root): 1 tsp tid

Safety

Contraindications: Pregnancy and lactation (uterine stimulant). Berberine is considered teratogenic.

Caution: Hypertension, gastritis, peptic ulcers.

Hypertension: Caution use due to hypertensive and hypotensive effects; monitor BP regularly.

†Gastritis, peptic ulcers: Stimulation of gastric secretions can irritate inflamed mucous membranes; concomitant ingestion of demulcent herbs can help prevent aggravation.

Interactions

• MDR pump inhibitors - contains a flavolignin that inhibits multi-drug resistance pumps, which are responsible for making bacteria resistant to certain antibiotics and cancer resistant to specific chemotherapeutic agents. Therefore it may be a good adjunctive herb to prevent and/or overcome drug resistance.

• Barbiturate - may potentiate their effects.

References

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Barnes J, Anderson LA, Phillipson JD. Herbal Medicines, 3rd ed. London: Pharmaceutical Press, 2007.

Bone K. Principles and Practice of Phytotherapy. Edinburgh: Churchill Livingstone, 2000.

Bone K. A Clinical Guide to Blending Liquid Herbs: Herbal Formulations for the Individual Patient. St Louis, MO: Churchill Livingstone, 2003.

Brinker F. The Toxicology of Botanical Medicines, 3rd ed. Sandy, Oregon: Eclectic Medical Publications, 2000.

Felter HW, Lloyd JU. King's American Dispensatory. 1898. http://www.ibiblio.org/herbmed/eclectic/kings/main.html. Accessed: August 19, 2006.

Hoffman D. Medical Herbalism. Rochester, Vermont: Healing Arts Press, 2003.

Weiss RF. Herbal Medicine. Beaconsfield, England: Beaconsfield Publishers Ltd, 1988.

Williamson EM, ed. Major Herbs of Ayurveda. Edinburgh: Churchill Livingstone, 2002

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