INFLA-GUARD TM

By : Douglas Laboratories

Indications

Infla-guard tablets provide a convenient combination of standardized extracts of Boswellia serrata, turmeric root, and Devil's Claw for individuals wishing to obtain the benefits of these complementary botanical extracts.

Ingredients

Two enteric-coated tablets contain:
Boswellia serrata, dried extract,
(min. 65% boswellin)...750 mg
Turmeric root, dried extract,
(min. 95% total curcuminoids) ...750 mg
Devil's Claw, dried extract,
(min. 5% harpagosides) ...100 mg

Description

DESCRIPTION
Infla-guardTM tablets, provided by Douglas Laboratories®, contain a synergistic combination of three standardized botanical extracts: Boswellia serrata, turmeric root, and Devil's Claw. Infla-guard tablets are coated with an acid-resistant enteric coating to protect the integrity of the Devil's Claw extract which may lose effectiveness when exposed to hydrochloric acid in the stomach.

FUNCTIONS
Infla-guard is a blend of three standardized botanical extracts which work together to help support the body's natural inflammatory responses. The combined actions of these extracts helps support and protect the body's connective tissues, such as tendons, ligaments, and cartilage. Boswellia serrata extract: Purified oleoresin from the Boswellia serrata tree, native to India, contains boswellic acids, which have been shown to be responsible for the tissue-protective actions of this extract. Boswellic acids appear to act by inhibiting of leukotrienes, a class of mediators of the body's inflammatory response. Boswellic acids are reported to increase blood supply to joint tissues, thereby preventing decline of cartilage synthesis. The extract from Boswellia serrata resin, standardized to contain a minimum of 65% boswellin, is an integral component of Infla-guard tablets. Turmeric root extract: Curcumin is the yellow pigment contained in turmeric (Curcuma longa), a popular culinary spice from India. In addition to imparting a characteristic color and flavor to foods, curcumin has potent antioxidant properties and beneficial action on tissue health. Like boswellic acids, curcumin inhibits mediators of the inflammatory response, including thromboxanes and leukotrienes. As an antioxidant, curcumin protects against oxidative damage. Additionally, there is evidence that curcumin may strengthen the body's natural antiinflammatory responses.
Devil's Claw extract: The tubers of this South African plant are rich in iridoid glycosides, in particular harpagosides. The harpagosides benefit connective tissue metabolism by supporting natural immune response to inflammation.

Quantity

60 tablets

Dose

Two tablets daily as a dietary supplement or as directed by a physician.

Potential side effects/Safety

SIDE EFFECTS
No adverse effects have been reported.

Keep out of reach of children.

References

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Ammon HP, Safayhi H, Mack T, Sabieraj J. Mechanism of antiinflammatory actions of curcumine and boswellic acids. J Ethnopharmacol 1993;38(2-3):113-119.
Joe B, Rao ZUJ, Lokesh BR. Presence of an acidic glycvoprotein in the serum of arthritic rats: modulation by capsaicin and curcumin. Mol Cell biochem 1997;169(1-2):125-134. Krishnaswamy K, et al. Retardation of experimental tumorigenesis and reduction in DNA adducts by turmeric and curcumin. Nutr Cancer 1998;30(2):163-166.
Kulkarni RR, et al. Treatment of osteoarthritis with an herbomineral formulation: a double blind, placebo-controlled, cross-over study. J Ethnopharmacol 1991;33(1-2):91-95.Reddy GK, Chandrakasan G, Dhar SC. Studies on themetabolism of glycosaminoglycans under the influence of new herbal antiinflammatory agents. Biochem Pharmacol 1989;38(20):3527- 3534.
Safayhi H, et al. Boswellic acids: novel, specific, nonredox inhibitors of 5-lipoxygenase. J Pharacol Exp Ther 1992;261 (3):1143-1146.
Safayhi H, Sailer ER, Ammon HP. Mechanism of 5-lipoxygenase inhibition by acetyl-11-keto-beta-boswellic acid. Mol Pharmacol1995;47(6):1212-1216.
Singh GB, Atal CK. Pharmacology of an extract of salai guggal ex-Boswellia serrata, a new non- steroidal antiinflammatory agent. Agents Actions 1986;18(3-4):407-412.
Srivastava R. Agents Actions 1989;28(3-4):298-303.

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