• In a base of organic flaxseed oil and organic olive oil for improved intestinal absorption
• Vitamin D3 (cholecalciferol) likely more effective at restoring blood levels than D2 form (ergocalciferol)
• Neutral taste
• Preserved with natural vitamin E
• Liquid form is convenient for a wide range of doses
• 500 drops per bottle
Serving Size: 1 drop (0.03 mL)
Servings per Container: 500
1 Drop Provides: 1000 IU Vitamin D3 (cholecalciferol) (lanolin)
Certified organic extra-virgin olive oil, organic flaxseed oil, natural vitamin E.
Contains no artificial preservatives, colours or sweeteners and no corn, dairy, starch, wheat or yeast.
Vitamin D is a hormone now widely recognized to be important to many body systems and a large number of physiological processes, and it may also be one of the most common nutrient deficiencies in the world. Many recent studies have linked lower levels to an increased risk of cardiovascular disease, including hypertension, peripheral vascular disease, coronary artery disease, and heart failure, as well as several types of cancer, autoimmune disease, and type 2 diabetes. Vitamin D is needed for intestinal calcium absorption, skeletal bone integrity as well as skeletal muscle strength and function, and has been associated with overall physical fitness. Vitamin D is critical for healthy immune function, and may reduce the risk of infection, especially respiratory tract infections. Given that essentially every tissue in the body has a receptor for vitamin D, it is hard to overestimate its importance. Many practitioners recommend supplementation to achieve blood levels of 25-OH-vitamin D between 50-80 nmol/L, which often requires doses of 1000-2000 IU per day, and more for those with common genetic variants affecting vitamin D metabolism.
15 mL (500 Drops per Bottle)
1 serving/drop (0.03 mL) per day or as directed by a health care professional. Shake before use. Keep out of reach of children.
Potential side effects/Safety
Caution is advised for individuals with a hypersensitivity to any of the ingredients, sarcoidosis, lymphoma, tuberculosis, hypercalcemia, or renal impairment.
When taken with a thiazide medication (diuretic), may increase the risk for hypercalcemia. Also, vitamin D may improve insulin sensitivity and lower blood pressure, requiring a reduction in dosage of hypertension and/or diabetic medications.
References:1.Holick MF. Vitamin D deficiency. N Engl J Med. 2007 Jul 19;357(3):266-81.
2.Muscogiuri G, Sorice GP, Ajjan R, Mezza T, Pilz S, Prioletta A, Scragg R, Volpe SL, Witham MD, Giaccari A. Can vitamin D deficiency cause diabetes and cardiovascular diseases? Present evidence and future perspectives. Nutr Metab Cardiovasc Dis. 2012 Feb;22(2):81-7.
3.Fletcher JM, Basdeo SA, Allen AC, Dunne PJ. Therapeutic use of vitamin D and its analogues in autoimmunity. Recent Pat Inflamm Allergy Drug Discov. 2012 Jan;6(1):22-34.
4.Baz-Hecht M, Goldfine AB. The impact of vitamin D deficiency on diabetes and cardiovascular risk. Curr Opin Endocrinol Diabetes Obes. 2010 Apr;17(2):113-9.
5.Gennari C. Calcium and vitamin D nutrition and bone disease of the elderly. Public Health Nutr. 2001 Apr;4(2B):547-59.
6.Udowenko M, Trojian T. Vitamin D: extent of deficiency, effect on muscle function, bone health, performance, and injury prevention. Conn Med. 2010 Sep;74(8):477-80.
7.Bartoszewska M, Kamboj M, Patel DR. Vitamin D, muscle function, and exercise performance. Pediatr Clin North Am. 2010 Jun;57(3):849-61.
8.Schwalfenberg GK. A review of the critical role of vitamin D in the functioning of the immune system and the clinical implications of vitamin D deficiency. Mol Nutr Food Res. 2011 Jan;55(1):96-108.
9.Bartley J. Vitamin D, innate immunity and upper respiratory tract infection. J Laryngol Otol. 2010 May;124(5):465-9.
10. Haussler MR, Jurutka PW, Mizwicki M, Norman AW. Vitamin D receptor (VDR) mediated actions of 1a,25(OH)2 vitamin D3: genomic and non-genomic mechanisms. Best Pract Res Clin Endocrinol Metab. 2011 Aug;25(4):543-59.
11.Boulard JC, Hanslik T, Alterescu R, Baglin A. [Symptomatic hypercalcemia after vitamin D-thiazide diuretics combination. Two cases in elderly women]. Presse Med. 1994 Jan 22;23(2):96.
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