products aor digestase-2-0

Digestase 2.0

By : AOR - Advanced Orthomolecular Research


• Digestion
• Gastrointestinal health
• Nutrient absorption


Supplement Facts
Serving Size:1 Capsule

Amylase (from Aspergillus oryzae) … 3,000 DU* / 75 mg
Protease (from A. oryzae) … 20,200 HUT* / 40.4 mg
Protease (from Aspergillus niger) … 10.1 SAP* / 9.4 mg …
Alpha Galactosidase (from A. niger) … 86.67 GalU* / 8.7 mg …
Invertase (from Saccharomyces cerevisiae) … 400 SU* / 4 mg …
Lactase (from A. oryzae) … 3000 ALU* / 30 mg …
Lipase (from A. niger and Rhizopus oryzae) … 250 LU* / 12.5 mg …
Cellulase (from A. niger) … 600 CU* / 8 mg …

*FCC-approved units.
Non-medicinal ingredients: microcrystalline cellulose, maltodextrin. Capsule: hypromellose.

AOR Guarantees: that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, nuts, dairy, soy, eggs, fish, shellfish or any animal byproduct.

Source: Biological fermentation


Digestase 2.0 is a vegetarian enzymatic digestive aid formulated with proteases and other digestive enzymes that activate at different pH ranges. Digestase 2.0 helps reduce gas production and prevent gastrointestinal intolerance caused by fermentable carbohydrates, assists in the digestion of lactose and helps prevent symptoms of lactose intolerance.

• Improves nutrient absorption
• Supports gastrointestinal health
• Improves digestion

Background Information
The Burden of Digestion The digestive system is essential to health. The digestion of foods requires the help of many different enzymes. Recent research has discovered that supplementation with these enzymes can help with digestion, improve the health of the gastrointestinal system, enhance nutrient absorption and alleviate the gastrointestinal burden of digesting food.
Optimal Activity Digestase is a formula based on the most advanced study of the human digestive system. It contains a mixture of digestive enzymes from a variety of sources to guarantee their function at different pH ranges, and to ensure healthy digestion.

The proteins, fats, polysaccharides and other nutrients that we consume in our foods cannot be used by our bodies as such, but must first be broken down into smaller units. This process requires the help of many enzymes found in the mouth, stomach, pancreas and intestines.

The principle behind digestive enzyme formulations is simple: to improve digestion and to alleviate the gastrointestinal burden of digesting the food we eat. AOR's latest enzyme supplement has been rigorously assessed in an experimental model designed to replicate human digestion. Digestase is a vegetarian and comprehensive enzyme formula with the basic premise of enhancing the digestion of food. The formula contains five different types of enzymes: two sources of protease and three different sources of lipase to broaden activity and ensure viability under a variety of pH profiles.

Enzymes for Eating Digestase contains a mixture of several enzymes critical to digestion. Amylase is needed to break up long-chain polysaccharides, protease is responsible for breaking down complex proteins, and lipase digests fats. Glucoamylase is required to break down carbohydrates while invertase breaks down sucrose. Besides improving digestion, these enzymes can also reduce inflammation, and have been shown to speed up recovery times after injury.

Using a new technology that replicates the human stomach and small intestines, the efficacy of Digestase as a digestive aid was assessed. Digestase supplementation improved the following digestive processes:

Under normal digestive conditions: Digestase more than doubled the absorption of carbohydrates and increased the absorption of protein in the ileum while protein absorption remained essentially the same in the jejunum.

Under impaired digestive conditions: differences were even greater: glucose absorption in the jejunum increasing 9-fold and protein digestion increasing significantly in both the jejunum and ileum.

The health benefits of enzyme supplementation are not limited to the absorption of nutrients. Supplemental enzymes relieve digestive organs. Animal experiments are clear: enzyme supplementation results in a healthier intestinal brush border and better nutrient accretion.
Supplemental enzymes also reduce inflammation and speed up recovery. Studies in athletes have shown improved recovery time when supplementing with enzymes. Similarly, patients undergoing surgery recover more quickly if they are prescribed enzymes. Enzymes facilitate chemical reactions, improve digestion, support digestive organs and hasten recovery. For the first time, a digestive enzyme has been tested and shown to support digestion.

Market Trends
Digestive enzymes are generally used by those who are interested in improving their digestive and overall health condition. Not all enzyme formulas are comprehensive and include effective amounts of enzymes to benefit digestive health. Enzymes are also increasing in popularity for the purposes of reducing inflammation and healing scar tissue.

AOR Advantage
DigestaseTM is formulated based on extensive and up to date scientific research conducted by a European Research Organization called TNO, in the most advanced study on the human digestive system. This formula contains two types of proteases that are activated at different PH ranges in order to facilitate guaranteed protein digestion. In total, five types of enzymes are included in the formula to enhance overall digestion and nutrient absorption. This formula also provides anti-inflammatory benefits. Digestase is the world's first digestive enzyme supported by research.


90 Vegi-Caps
188 mg


Take 1 capsule three times a day with food or as directed by a qualified health practitioner.

Potential side effects/Safety

Cautions: Consult a health care practitioner for prolonged use, or prior to use if you have gastrointestinal lesions/ulcers, diabetes, if you are having surgery, or if you are taking anticoagulants, anti-inflammatories or other enzyme products. Discontinue use and consult a health care practitioner if symptoms persist or worsen. Headaches, heartburn, bloating and hypersensitivity (e.g. allergy) have been known to occur; in which case, discontinue use.

Pregnancy/Nursing: Do not take


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Lomax E. The use of oral proteolytic enzymes in the post-lipoplasty patient. Case report (unpublished)

Meng X, Slominski BA, Guenter W. The effect of fat type, carbohydrase, and lipase addition on growth performance and nutrient utilization of young broilers fed wheat-based diets. Poult Sci. 2004 Oct;83(10):1718-27.

Miller PC, Bailey SP, Barnes ME, Derr SJ, Hall EE. The effects of protease supplementation on skeletal muscle function and DOMS following downhill running. J Sports Sci. 2004 Apr;22(4):365-72.

Ritz CW, Hulet RM, Self BB, Denbow DM. Growth and intestinal morphology of male turkeys as influenced by dietary supplementation of amylase and xylanase. Poult Sci. 1995 Aug;74(8):1329-34.

Zeijdner E, Havenaar R, (2000). The Fate of orally administered compounds during passage through the gastrointestinal tract simulated in a dynamic in vitro model (TIM). European pharmaceutical Contractor, Febr. Isue: 76-81

Zeijdner E, Mohede R, I.C.M. (1999). Latest tool for screening new clinical foods. A dynamic, computer-controlled model of the human gastrointestinal tract is the most up-to-date technology for testing new foods. New World Health 199-2000: 105.a

Disclaimer: This content is subject to change. The information is intended to inform and educate; it does not replace the medical evaluation, advice, diagnosis or treatment by a healthcare professional. © 2015 NDAssist Inc. and/or its affiliates. All rights reserved.